Milan to Florence: Parmesan, Pisa & Chianti
- Balsamic vinegar tasting in Modena
- Parmigiano Reggiano dairy visit with lunch
- Guided walks in Pisa, Lucca and Siena
Milan's Gothic marble cathedral and Leonardo's Last Supper at Santa Maria delle Grazie
Milan's two most famous sights sit a short metro ride apart. In the city's central square, the Duomo rises in a forest of white marble pinnacles and statues, and visitors can walk among its spires on the rooftop terraces with views over the city. Inside, vast columns and stained glass create a cool, solemn space in the heart of Italy's busiest commercial city.
A little to the west, the Dominican convent of Santa Maria delle Grazie guards Leonardo da Vinci's Last Supper, painted on the wall of the friars' former dining hall. Seeing it requires advance booking, but the brief, quiet encounter with this fragile masterpiece is one of the most memorable art experiences in Italy.
Construction of the Duomo began in 1386 under Archbishop Antonio da Saluzzo, with strong support from Gian Galeazzo Visconti, who became Duke of Milan in 1395 and granted the cathedral marble from the Candoglia quarry in perpetuity. Work continued for centuries: the main spire topped by the gilded Madonnina was erected in 1762, and the last portal was inaugurated in 1965. Dedicated to the Nativity of St Mary, it is the largest church in the Italian Republic.
Santa Maria delle Grazie was begun in 1463 and reworked by Bramante at the end of the 15th century. Leonardo painted the Last Supper on the refectory's north wall between 1495 and 1497, using tempera on plaster rather than true fresco, which has caused conservation problems ever since. The building was badly damaged by bombing in 1943, but the painting survived. UNESCO inscribed the church and convent with the Last Supper in 1980.
The Duomo is the spiritual and social heart of Milan: Milanese meet on its square, festivals and concerts take place in front of it, and the Madonnina on its highest spire is a beloved symbol of the city. The cathedral is still an active church, as is Santa Maria delle Grazie, where Dominican friars have held the complex in concession since 1934. Around them, Milan's fashion, design and business life carry on at a brisk pace.
Visit the Duomo early, then take the lift or stairs to the terraces to walk among the spires and statues, with views across Milan and, on clear days, towards the Alps. Back on the square, stroll through the glass-roofed Galleria Vittorio Emanuele II to Piazza della Scala.
For the Last Supper, book your timed slot well ahead and arrive at least half an hour early. Visits are limited to small groups for 15 minutes in a climate-controlled room, so take a moment to study the expressions and gestures of the apostles. Afterwards, look around the church of Santa Maria delle Grazie and its peaceful cloister.
Spring and autumn are the most comfortable seasons for sightseeing and rooftop views. Summer can be hot and humid, making early terrace visits more pleasant, while August is quieter as many residents take holidays. Winter brings shorter days and occasional fog, but the cathedral is atmospheric during the Christmas season. The Last Supper requires booking whatever the season.
Checked against the sources on 27 October 2026. Opening times and fees can change — confirm before you go.
General guidance from our specialists, not official information.
Galleria Vittorio Emanuele II and Piazza della Scala adjoin the cathedral square, and the Brera district and Castello Sforzesco are within walking distance. Santa Maria delle Grazie stands at Piazza Santa Maria delle Grazie 2, west of the cathedral. Milan Centrale station has high-speed trains to Florence, Rome and Venice, and the city has a wide range of accommodation around the centre.
This guide was researched from the sources below and reviewed by our team on 27 October 2026. Facts under “Verified information” link to the page they were checked on; travel tips are general guidance. Photos are credited on each image.